Description

4-Phenyl-2,8-diazaspiro[4.5]decan-1-one hydrochloride is a high-purity, advanced pharmaceutical intermediate belonging to the spirocyclic compound class. This compound is valued for its complex molecular architecture, which serves as a critical building block in modern medicinal chemistry and drug discovery programs. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutic agents, particularly within the central nervous system (CNS) and other specialized therapeutic areas.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of new active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used as a core scaffold or building block for constructing compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• Drug Discovery: Employed in the synthesis of potential drug candidates targeting neurological receptors and other biological pathways.
• Chemical Synthesis: Serves as a versatile intermediate for further functionalization and the creation of more complex molecular entities.
• Academic & Contract Research: Utilized in university laboratories and contract research organizations (CROs) for exploratory chemical and pharmacological research.

Basic Information

Product Name	4-Phenyl-2,8-diazaspiro[4.5]decan-1-one hydrochloride
CAS No.	1198284-29-5
Molecular Formula	C15H19N2O·HCl
Molecular Weight	280.79 g/mol (Free base: 243.33 g/mol)
Synonyms	4-Phenyl-2,8-diazaspiro[4.5]decan-1-one HCl; 1-Oxo-4-phenyl-2,8-diazaspiro[4.5]decane hydrochloride; 4-Phenyl-2,8-diazaspiro[4.5]decan-1-one monohydrochloride; 4-Phenyl-1-oxo-2,8-diazaspiro[4.5]decane hydrochloride; 2,8-Diazaspiro[4.5]decan-1-one, 4-phenyl-, hydrochloride; Spiro[4.5]decan-1-one, 4-phenyl-2,8-diaza-, hydrochloride
EINECS	Contact for details

Quality Control

Our 4-Phenyl-2,8-diazaspiro[4.5]decan-1-one hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and moisture content, to ensure it meets the stringent requirements for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability, consistency, and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under inert conditions or in a desiccator to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.