Description

Allyl 3-Hydroxyazetidine-1-Carboxylate is a versatile azetidine derivative that serves as a crucial building block in advanced organic synthesis. This compound is valued for its bifunctional structure, featuring both a reactive allyl ester and a hydroxy-substituted azetidine ring, enabling its use in the construction of complex molecular architectures. It is primarily sought by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and fine chemical manufacturing.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in protease inhibitor and other small-molecule drug discovery programs.
• Agrochemical Synthesis: Used in the research and production of advanced crop protection agents and herbicides, leveraging the azetidine scaffold's bioactivity.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Polymer Chemistry: Acts as a monomer or cross-linking agent for specialty polymers with tailored properties.
• Chemical Biology Probes: Utilized in the synthesis of molecular probes for studying enzyme function and biological pathways.
• Peptidomimetics: The azetidine core is a valuable constrained scaffold for designing peptide mimics with enhanced metabolic stability.

Basic Information

Product Name	Allyl 3-Hydroxyazetidine-1-Carboxylate
CAS No.	1198283-27-0
Molecular Formula	C7H11NO3
Molecular Weight	157.17 g/mol
Synonyms	1-(Allyloxycarbonyl)-3-hydroxyazetidine; 3-Hydroxyazetidine-1-carboxylic Acid Allyl Ester; Allyl 3-Hydroxy-1-azetidinecarboxylate; Azetidin-3-ol, 1-(2-propen-1-yloxycarbonyl)-; 1-Carboxy-3-hydroxyazetidine Allyl Ester
EINECS	Contact for details

Quality Control

Every batch of Allyl 3-Hydroxyazetidine-1-Carboxylate is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and development. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment. Our quality protocols are designed to support cGMP (current Good Manufacturing Practice) compliance for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. Keep away from strong bases and incompatible organic solvents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.