Description

8-Chloro-1H-Pyrido[2,3-B][1,4]Oxazin-2(3H)-One is a high-purity heterocyclic organic compound, identified by CAS NO 1198154-62-9, serving as a critical advanced pharmaceutical intermediate. Its value lies in its role as a sophisticated building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex molecular architectures. This compound is essential for research and development chemists, process chemists, and manufacturers in the pharmaceutical and biotechnology industries who are developing next-generation drug candidates.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of complex drug molecules, particularly for central nervous system (CNS) and oncology targets.
• Medicinal Chemistry Research: Used in high-throughput screening and structure-activity relationship (SAR) studies to develop new therapeutic agents.
• Process Chemistry & Scale-Up: Serves as a starting material or intermediate in the development and optimization of scalable API manufacturing routes.
• Bioconjugation & Probe Development: Potential utility in creating chemical probes or tagged molecules for biochemical and diagnostic research.
• Contract Research & Manufacturing (CRAM): Supplied to organizations specializing in custom synthesis and development services.

Basic Information

Product Name	8-Chloro-1H-Pyrido[2,3-B][1,4]Oxazin-2(3H)-One
CAS No.	1198154-62-9
Molecular Formula	C7H5ClN2O2
Molecular Weight	184.58 g/mol
Synonyms	8-Chloro-1H,2H,3H-pyrido[2,3-b][1,4]oxazin-2-one; 8-Chloro-3,4-dihydro-1H-pyrido[2,3-b][1,4]oxazin-2-one; 8-Chloro-2,3-dihydro-1H-pyrido[2,3-b][1,4]oxazin-2-one; 8-Chloro-1H-pyrido[2,3-b][1,4]oxazine-2(3H)-one; 1198154-62-9; 8-Chloro-3,4-dihydro-2H-pyrido[2,3-b][1,4]oxazin-2-one
EINECS	Contact for details

Quality Control

Our 8-Chloro-1H-Pyrido[2,3-B][1,4]Oxazin-2(3H)-One is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and pharmaceutical development. All batches are accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We support development with custom synthesis and analytical method development to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). The container should be kept tightly sealed in a dry environment to protect the compound from moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.