Description

tert-Butyl 7-Iodo-2H-Pyrido[3,2-B][1,4]Oxazine-4(3H)-Carboxylate is a high-purity, advanced pharmaceutical intermediate featuring a halogenated pyridooxazine core structure. This compound is a critical building block in modern medicinal chemistry, enabling the synthesis of complex molecules with potential therapeutic activity. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex heterocyclic compounds for drug discovery and development programs.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization, particularly in oncology and CNS drug research.
• API Synthesis: Serves as a crucial building block in the multi-step synthesis of potential Active Pharmaceutical Ingredients (APIs).
• Chemical Biology: Employed in the development of chemical probes and tool compounds for target validation and biological pathway investigation.
• Process Chemistry: Used in route scouting and scale-up studies for the efficient and cost-effective production of target molecules.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for the pharmaceutical industry.

Basic Information

Product Name	tert-Butyl 7-Iodo-2H-Pyrido[3,2-B][1,4]Oxazine-4(3H)-Carboxylate
CAS No.	1198108-82-5
Molecular Formula	C12H13IN2O3
Molecular Weight	360.15 g/mol
Synonyms	7-Iodo-3,4-dihydro-2H-pyrido[3,2-b][1,4]oxazine-4-carboxylic acid tert-butyl ester; tert-Butyl 7-iodo-3,4-dihydro-2H-pyrido[3,2-b][1,4]oxazine-4-carboxylate; 7-Iodo-3,4-dihydro-2H-pyrido[3,2-b][1,4]oxazine-4-carboxylic acid 1,1-dimethylethyl ester; 1198108-82-5; tert-Butyl 7-iodo-2H-pyrido[3,2-b][1,4]oxazine-4(3H)-carboxylate; BOC-protected 7-iodo-pyridooxazine
EINECS	Contact for details

Quality Control

Our tert-Butyl 7-Iodo-2H-Pyrido[3,2-B][1,4]Oxazine-4(3H)-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Assay	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.