Description

Methyl 4-({2-[(tert-Butoxycarbonyl)-Amino]Ethyl}Amino)-3-Nitrobenzoate is a high-purity, protected amino acid derivative and a key synthetic intermediate in advanced organic chemistry. This compound is valued for its role in constructing complex molecular architectures, particularly in peptide mimetics and pharmaceutical research. It is essential for R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries who require reliable building blocks for drug discovery and development.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for compounds targeting specific biological pathways.
• Peptidomimetic Research: Used to introduce protected aminoethylamino-nitrobenzoate motifs into peptide backbones to enhance stability, bioavailability, or receptor binding affinity.
• Protease Inhibitor Development: Serves as a core scaffold or side-chain component in the design and synthesis of protease enzyme inhibitors.
• Linker Chemistry in Bioconjugation: The reactive functional groups make it suitable for developing cleavable or non-cleavable linkers used in antibody-drug conjugates (ADCs) and other bioconjugates.
• Chemical Biology Probes: Employed in the creation of fluorescent or affinity tags for studying protein-protein interactions and cellular processes.
• Custom Synthesis & Contract Manufacturing: A specified intermediate for custom synthesis projects requiring high-purity, complex organic molecules.

Basic Information

Product Name	Methyl 4-({2-[(tert-Butoxycarbonyl)-Amino]Ethyl}Amino)-3-Nitrobenzoate
CAS No.	1198093-70-7
Molecular Formula	C15H21N3O6
Molecular Weight	339.35 g/mol
Synonyms	4-({2-[(tert-Butoxycarbonyl)amino]ethyl}amino)-3-nitrobenzoic acid methyl ester; Methyl 4-[(2-{[(tert-butoxy)carbonyl]amino}ethyl)amino]-3-nitrobenzoate; Boc-NH-(CH2)2-NH-3-NO2-C6H3-COOCH3; tert-Butyl N-[2-[(4-methoxycarbonyl-2-nitrophenyl)amino]ethyl]carbamate; Boc-EDA-3-nitro-4-methylbenzoate; 1198093-70-7
EINECS	Contact for details

Quality Control

Our Methyl 4-({2-[(tert-Butoxycarbonyl)-Amino]Ethyl}Amino)-3-Nitrobenzoate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports applications requiring GMP-grade intermediates and materials for regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed and under an inert atmosphere for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.