Description

1-[3-Chloro-5-(Trifluoromethyl)Pyridin-2-Yl]Homopiperazine Hydrochloride is a high-purity, advanced pharmaceutical intermediate with a defined heterocyclic structure. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular scaffolds. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and agrochemical industries for developing next-generation products.

Application

• Pharmaceutical Intermediate: A key building block for the research and synthesis of novel drug candidates, especially in central nervous system (CNS) and anti-infective therapeutic areas.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its pyridine and piperazine motifs for biological activity.
• Chemical Synthesis: Serves as a versatile precursor for further functionalization in medicinal chemistry and material science projects.
• Contract Research & Manufacturing (CRAM): Supplied to organizations specializing in custom synthesis and scale-up services for client-specific molecules.
• Academic & Institutional Research: Used in university and institutional labs for studying structure-activity relationships (SAR) and novel heterocyclic chemistry.

Basic Information

Product Name	1-[3-Chloro-5-(Trifluoromethyl)Pyridin-2-Yl]Homopiperazine Hydrochloride
CAS No.	1197238-46-2
Molecular Formula	C12H14ClF3N3•HCl
Molecular Weight	316.62 g/mol (as hydrochloride salt)
Synonyms	1-[3-Chloro-5-(trifluoromethyl)-2-pyridinyl]hexahydro-1H-1,4-diazepine hydrochloride; 1-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)homopiperazine HCl; 2-(Homopiperazin-1-yl)-3-chloro-5-(trifluoromethyl)pyridine hydrochloride; 1,4-Diazepine, 1-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]hexahydro-, hydrochloride (1:1)
EINECS	Contact for details

Quality Control

Our 1-[3-Chloro-5-(Trifluoromethyl)Pyridin-2-Yl]Homopiperazine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.