Description

4-Amino-2-Bromo-5-Fluoro-Benzoic Acid Methyl Ester is a high-purity, multifunctional aromatic building block essential for advanced organic synthesis. Its unique halogenated and aminated benzoate structure makes it a critical intermediate for developing active pharmaceutical ingredients (APIs) and agrochemicals. This compound is primarily targeted at research and development chemists and process scale-up teams in the pharmaceutical, agrochemical, and specialty chemical industries seeking reliable, high-quality intermediates for complex molecule construction.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in fluorinated and brominated active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides where the fluorine and bromine substituents enhance biological activity.
• Material Science Research: Serves as a precursor for functionalized monomers or ligands in the development of specialty polymers and advanced materials.
• Chemical Biology & Proteomics: Utilized as a derivatization agent or a scaffold for creating molecular probes and tags due to its reactive amino and ester functional groups.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis projects and contract research organizations (CROs/CMOs) specializing in fluorinated compounds.

Basic Information

Product Name	4-Amino-2-Bromo-5-Fluoro-Benzoic Acid Methyl Ester
CAS No.	1196693-85-2
Molecular Formula	C8H7BrFNO2
Molecular Weight	248.05 g/mol
Synonyms	Methyl 4-Amino-2-Bromo-5-Fluorobenzoate; 2-Bromo-5-Fluoro-4-Aminobenzoic Acid Methyl Ester; Benzoic acid, 4-amino-2-bromo-5-fluoro-, methyl ester; 4-Amino-2-bromo-5-fluorobenzoic acid methyl ester; Methyl 4-amino-2-bromo-5-fluorobenzoate
EINECS	Contact for details

Quality Control

Our 4-Amino-2-Bromo-5-Fluoro-Benzoic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for pharmaceutical and agrochemical applications. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive and should be stored away from light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.