Description

3-Chloro-4-Ethynylpyridine is a high-value pyridine derivative featuring both chloro and ethynyl functional groups, making it a versatile and reactive building block for advanced chemical synthesis. Its molecular structure is critical for constructing complex heterocyclic systems and functional materials. This compound is primarily sought after by research institutions and industrial R&D departments engaged in pharmaceutical development, agrochemical research, and materials science.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and plant growth regulators.
• Ligand and Catalyst Development: The ethynyl group allows for facile coupling reactions (e.g., Sonogashira), making it valuable for creating novel ligands for catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the development of organic electronic materials, conductive polymers, and advanced polymers with tailored properties.
• Chemical Biology Probes: Acts as a building block for creating molecular probes and tags used in bio-conjugation and diagnostic assay development.

Basic Information

Product Name	3-Chloro-4-Ethynylpyridine
CAS No.	1196156-71-4
Molecular Formula	C7H4ClN
Molecular Weight	137.57 g/mol
Synonyms	4-Ethynyl-3-chloropyridine; 3-Chloro-4-ethynylpyridine; 3-Chloro-4-pyridylethyne; 4-(Chloro)ethynylpyridine; Pyridine, 3-chloro-4-ethynyl-
EINECS	Contact for details

Quality Control

Our 3-Chloro-4-Ethynylpyridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and development. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and easily oxidized nature, it is recommended to handle and store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.