Description

tert-Butyl 6-Formylpyridin-3-Ylcarbamate is a high-purity, multifunctional chemical building block featuring both a formyl group and a protected amine, making it a versatile intermediate for advanced synthesis. Its primary value lies in enabling the efficient construction of complex molecules, particularly in pharmaceutical research and development. This compound is essential for medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to develop new active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly for kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides, leveraging its reactive aldehyde functionality.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in catalytic systems and metal-organic frameworks (MOFs).
• Peptidomimetic Research: The carbamate-protected amine and aldehyde group are valuable for constructing peptide analogs and other bio-inspired molecules.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and target engagement.
• Custom Synthesis and Contract Manufacturing: A critical building block for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the global life sciences market.

Basic Information

Product Name	tert-Butyl 6-Formylpyridin-3-Ylcarbamate
CAS No.	1196156-55-4
Molecular Formula	C11H14N2O3
Molecular Weight	222.24 g/mol
Synonyms	tert-Butyl (6-formylpyridin-3-yl)carbamate; 5-[[(tert-Butoxy)carbonyl]amino]-2-pyridinecarboxaldehyde; 3-Pyridinecarboxaldehyde, 5-[[(1,1-dimethylethoxy)carbonyl]amino]-; BOC-6-Formyl-3-aminopyridine; N-Boc-5-amino-2-pyridinecarboxaldehyde; tert-Butyl 5-amino-2-pyridinecarboxylate N-Boc derivative; 6-Formylpyridin-3-amine, N-Boc protected
EINECS	Contact for details

Quality Control

Our tert-Butyl 6-Formylpyridin-3-Ylcarbamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is easily oxidized; for long-term storage, it is recommended to keep the material under an inert atmosphere (e.g., nitrogen or argon) to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.