Description

2-Chloro-3-Fluoro-4-Pyridinecarboxaldehyde Hydrate is a high-value, multi-functional heterocyclic building block essential for advanced organic synthesis. Its core value lies in the strategic positioning of reactive aldehyde and halogen substituents on the pyridine ring, enabling precise molecular construction. This compound is critically needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides, leveraging its halogenated pyridine scaffold.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized chelating ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of functionalized polymers and organic electronic materials.
• Chemical Biology Probes: Utilized to build molecular probes for studying biological pathways and protein interactions.
• Custom Synthesis and Contract Manufacturing: A fundamental building block for custom synthesis projects requiring complex, fluorinated heterocycles.

Basic Information

Product Name	2-Chloro-3-Fluoro-4-Pyridinecarboxaldehyde Hydrate
CAS No.	1196156-07-6
Molecular Formula	C6H3ClFNO • xH2O
Molecular Weight	159.54 (Anhydrous basis)
Synonyms	4-Pyridinecarboxaldehyde, 2-chloro-3-fluoro-, hydrate; 2-Chloro-3-fluoro-4-formylpyridine hydrate; 2-Chloro-3-fluoropyridine-4-carbaldehyde hydrate; 3-Fluoro-2-chloro-4-pyridinecarboxaldehyde hydrate; 2-Chloro-3-fluoroisonicotinaldehyde hydrate; 4-Formyl-2-chloro-3-fluoropyridine hydrate
EINECS	Contact for details

Quality Control

Our 2-Chloro-3-Fluoro-4-Pyridinecarboxaldehyde Hydrate is produced under strict quality management protocols. Each batch undergoes comprehensive analytical characterization, including HPLC for purity, NMR for structural confirmation, and KF titration for water content, to ensure it meets the stringent requirements of research and process chemistry. Certificates of Analysis (COA) with full analytical data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.