Description

3-Bromo-5,6,7,8-tetrahydro-1,7-naphthyridine is a high-value brominated heterocyclic building block of significant interest in advanced organic synthesis. Its core structure makes it a critical intermediate for constructing complex molecules with tailored biological and material properties. This compound is primarily utilized by research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries for applications such as medicinal chemistry and ligand development.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and oncology targets.
• Medicinal Chemistry: Used in structure-activity relationship (SAR) studies and lead optimization campaigns due to its versatile bromine handle for cross-coupling reactions.
• Agrochemical Research: Serves as a building block for developing new crop protection agents and herbicides.
• Ligand Synthesis: Employed in the preparation of complex ligands for catalysis and material science applications.
• Chemical Biology: Used as a probe or tag in biochemical research to study protein interactions and enzyme function.
• Academic & Contract Research: A valuable reagent for universities and CROs (Contract Research Organizations) exploring new synthetic methodologies and heterocyclic chemistry.

Basic Information

Product Name	3-Bromo-5,6,7,8-tetrahydro-1,7-naphthyridine
CAS No.	1196156-01-0
Molecular Formula	C8H9BrN2
Molecular Weight	213.08 g/mol
Synonyms	3-Bromo-5,6,7,8-tetrahydro-1,7-naphthyridine; 1,7-Naphthyridine, 3-bromo-5,6,7,8-tetrahydro-; 3-Bromo-1,2,3,4-tetrahydro-1,7-naphthyridine; 3-Bromotetrahydro-1,7-naphthyridine; 3-Bromo-5,6,7,8-tetrahydro-[1,7]naphthyridine
EINECS	Contact for details

Quality Control

Our 3-Bromo-5,6,7,8-tetrahydro-1,7-naphthyridine is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.