Description

Furo[2,3-B]Pyridin-3(2H)-One, 6-(Trifluoromethyl)- is a high-value heterocyclic building block distinguished by its fused furan-pyridinone core and trifluoromethyl substituent. This compound matters for its role as a critical synthetic intermediate in modern pharmaceutical and agrochemical research, enabling the introduction of desirable physicochemical properties. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing novel active molecules.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in kinase inhibitor and antiviral research programs.
• Agrochemical Research: Used in developing advanced active ingredients for crop protection, leveraging the stability and bioactivity of the trifluoromethyl group.
• Material Science: Serves as a precursor for specialty chemicals and functional materials requiring specific heterocyclic architectures.
• Chemical Biology: Employed as a molecular probe or scaffold in the design of enzyme inhibitors and receptor modulators.
• Process Chemistry: Utilized in route scouting and optimization for the scalable production of complex target molecules.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs offering bespoke chemical synthesis services.

Basic Information

Product Name	Furo[2,3-B]Pyridin-3(2H)-One, 6-(Trifluoromethyl)-
CAS No.	1196155-86-8
Molecular Formula	C8H4F3NO2
Molecular Weight	203.12 g/mol
Synonyms	6-(Trifluoromethyl)furo[2,3-b]pyridin-3(2H)-one; 6-(Trifluoromethyl)-2,3-dihydrofuro[2,3-b]pyridin-3-one; 6-Trifluoromethyl-3H-furo[2,3-b]pyridin-3-one; 6-(Trifluoromethyl)-3H-furo[2,3-b]pyridin-3-one; 1196155-86-8; Furo[2,3-b]pyridin-3(2H)-one, 6-(trifluoromethyl)-; AS-13879; ZINC000253849793
EINECS	Contact for details

Quality Control

Our Furo[2,3-B]Pyridin-3(2H)-One, 6-(Trifluoromethyl)- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our quality commitment supports compliance with the standards required for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.