Description

4-Bromo-2-Ethynylpyridine is a versatile and high-value pyridine derivative containing both bromo and ethynyl functional groups, making it a crucial building block for advanced organic synthesis. Its primary value lies in its dual reactivity, enabling efficient cross-coupling reactions and cycloadditions to construct complex heterocyclic scaffolds. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides with specific modes of action.
• Material Science: Serves as a monomer or cross-linking agent for creating specialized polymers, conductive materials, and metal-organic frameworks (MOFs).
• Ligand Synthesis: Employed to construct sophisticated nitrogen-containing ligands for catalysis and coordination chemistry.
• Chemical Research: A valuable reagent for exploring Sonogashira, Suzuki-Miyaura, and other palladium-catalyzed cross-coupling reactions.
• Fluorescent Probe Development: Used as a core structure for synthesizing organic fluorophores and sensing materials.

Basic Information

Product Name	4-Bromo-2-Ethynylpyridine
CAS No.	1196155-22-2
Molecular Formula	C7H4BrN
Molecular Weight	182.02 g/mol
Synonyms	2-Ethynyl-4-bromopyridine; 4-Bromo-2-ethynylpyridine; 4-Bromo-2-pyridylacetylene; 2-(4-Bromopyridin-2-yl)acetylene; Pyridine, 4-bromo-2-ethynyl-; 4-Bromo-2-ethinylpyridine
EINECS	Contact for details

Quality Control

Our 4-Bromo-2-Ethynylpyridine is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to verify identity and purity. A Certificate of Analysis (COA) detailing all test results is provided with every shipment, ensuring full traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.