Description

tert-Butyl 6,7-Dihydro-1-Methyl-1H-Pyrrolo[3,2-C]Pyridine-5(4H)-Carboxylate is a high-purity, advanced pharmaceutical intermediate belonging to the fused pyrrolopyridine class of heterocyclic compounds. This compound is a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), valued for its precise molecular architecture that enables targeted drug development. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the discovery and production of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of new drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• API Synthesis: Serves as a crucial building block in the multi-step synthesis of complex Active Pharmaceutical Ingredients (APIs) requiring the fused pyrrolopyridine scaffold.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes to develop compounds with improved efficacy and safety profiles.
• Process Chemistry & Scale-Up: Employed in route scouting and process development for the efficient, scalable manufacturing of target molecules.
• Biochemical Tool Compound: Can be utilized in biochemical assays and as a probe to study specific biological pathways and enzyme interactions.
• Custom Synthesis & Contract Manufacturing: A starting material for custom synthesis services catering to the specific needs of pharmaceutical and biotech companies.

Basic Information

Product Name	tert-Butyl 6,7-Dihydro-1-Methyl-1H-Pyrrolo[3,2-C]Pyridine-5(4H)-Carboxylate
CAS No.	1196154-76-3
Molecular Formula	C14H20N2O2
Molecular Weight	248.32 g/mol
Synonyms	1-Methyl-4,5,6,7-tetrahydro-1H-pyrrolo[3,2-c]pyridine-5-carboxylic acid tert-butyl ester; tert-Butyl 1-methyl-4,5,6,7-tetrahydro-1H-pyrrolo[3,2-c]pyridine-5-carboxylate; 5-tert-Butoxycarbonyl-1-methyl-4,5,6,7-tetrahydro-1H-pyrrolo[3,2-c]pyridine; 1-Methyl-1,4,5,6,7,8-hexahydropyrrolo[3,2-c]pyridine-5-carboxylic acid tert-butyl ester; BOC-1-Methyl-4,5,6,7-tetrahydro-1H-pyrrolo[3,2-c]pyridine-5-carboxylate
EINECS	Contact for details

Quality Control

Our tert-Butyl 6,7-Dihydro-1-Methyl-1H-Pyrrolo[3,2-C]Pyridine-5(4H)-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and structural identity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specification results. Our production adheres to cGMP guidelines where applicable, ensuring reliable quality and batch-to-batch consistency for critical pharmaceutical development work.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed and stored away from direct light and moisture sources to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.