Description

Methyl 2-(4-Aminophenyl)-2-Bromoacetate is a specialized brominated aromatic ester building block featuring both an amino and an ester functional group. This unique bifunctional structure makes it a valuable intermediate for synthesizing more complex molecules in advanced chemical research and development. It is primarily sought after by pharmaceutical and agrochemical R&D teams for constructing active pharmaceutical ingredients (APIs) and novel crop protection agents. The compound's reactivity profile allows for selective modifications, enabling the creation of targeted libraries for drug discovery and material science applications.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly in the development of small molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, leveraging its aromatic amine core.
• Organic Synthesis & Research: Serves as a versatile precursor for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic substitution reactions.
• Material Science: Potential monomer or modifier in the development of specialty polymers and advanced organic materials.
• Chemical Biology: Useful as a probe or linker in bioconjugation chemistry due to its reactive bromoacetate moiety.

Basic Information

Product Name	Methyl 2-(4-Aminophenyl)-2-Bromoacetate
CAS No.	1196154-73-0
Molecular Formula	C9H10BrNO2
Molecular Weight	244.09 g/mol
Synonyms	Methyl α-Bromo-4-aminophenylacetate; 2-Bromo-2-(4-aminophenyl)acetic acid methyl ester; (4-Aminophenyl)bromoacetic acid methyl ester; Methyl (4-aminophenyl)bromoacetate; p-Aminophenylbromoacetic acid methyl ester; Methyl 2-bromo-2-(4-aminophenyl)acetate; Bromo(4-aminophenyl)acetic acid methyl ester
EINECS	Contact for details

Quality Control

Our production of Methyl 2-(4-Aminophenyl)-2-Bromoacetate adheres to stringent internal quality standards to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is characterized using advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.