Description

4-Bromo-6-Trifluoromethyl-Pyridin-2-Ylamine is a high-value, multi-functional halogenated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its core value lies in the strategic combination of bromine and trifluoromethyl groups on the pyridine ring, enabling precise molecular modifications for developing novel compounds with targeted properties. This intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for creating active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), especially in kinase inhibitor and antiviral drug discovery programs.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides, leveraging the bioactivity-enhancing trifluoromethyl group.
• Material Science Precursor: Employed in the synthesis of functional ligands for catalysis and advanced organic electronic materials.
• Cross-Coupling Reactions: The bromine substituent makes it an excellent substrate for Suzuki, Stille, and Buchwald-Hartwig amination reactions to construct complex biaryl systems.
• Chemical Biology Probes: Serves as a starting point for creating labeled compounds and molecular probes for biochemical research.
• Custom Synthesis & Contract Manufacturing: A fundamental building block for custom synthesis services targeting specialized and proprietary molecules.

Basic Information

Product Name	4-Bromo-6-Trifluoromethyl-Pyridin-2-Ylamine
CAS No.	1196147-49-5
Molecular Formula	C7H4BrF3N2
Molecular Weight	241.02 g/mol
Synonyms	2-Amino-4-bromo-6-(trifluoromethyl)pyridine; 4-Bromo-6-(trifluoromethyl)pyridin-2-amine; 4-Bromo-6-trifluoromethyl-2-pyridinamine; 2-Pyridinamine, 4-bromo-6-(trifluoromethyl)-; 4-Bromo-6-(trifluoromethyl)-2-aminopyridine; 4-Bromo-6-(trifluoromethyl)-2-pyridylamine
EINECS	Contact for details

Quality Control

Our 4-Bromo-6-Trifluoromethyl-Pyridin-2-Ylamine is produced under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates, ensuring reliability for your most demanding synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging during storage and handling.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.