Description

5-Chloro-2-Methoxypyridin-4-Ol is a versatile pyridine derivative that serves as a critical building block in advanced organic synthesis. This compound is valued for its unique substitution pattern, which makes it an essential intermediate for constructing complex molecules with specific pharmacological or agrochemical activities. It is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drug candidates targeting central nervous system (CNS) disorders, inflammation, and infectious diseases.
• Agrochemical Synthesis: Used in the development of new-generation herbicides, fungicides, and insecticides, where its pyridine core contributes to biological activity.
• Material Science Research: Serves as a monomer or functionalizing agent in the creation of specialty polymers, ligands for catalysis, and organic electronic materials.
• Chemical Biology & Proteomics: Employed as a building block for designing molecular probes, enzyme inhibitors, and tagged compounds for biochemical studies.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for use in custom synthesis projects and scale-up campaigns.

Basic Information

Product Name	5-Chloro-2-Methoxypyridin-4-Ol
CAS No.	1196146-71-0
Molecular Formula	C6H6ClNO2
Molecular Weight	159.57 g/mol
Synonyms	4-Hydroxy-5-chloro-2-methoxypyridine; 5-Chloro-2-methoxy-4-pyridinol; 5-Chloro-4-hydroxy-2-methoxypyridine; 2-Methoxy-5-chloropyridin-4-ol; 5-Chloro-4-pyridinol, 2-methoxy-; 4-Pyridinol, 5-chloro-2-methoxy-; 1196146-71-0
EINECS	Contact for details

Quality Control

Our 5-Chloro-2-Methoxypyridin-4-Ol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials. This material is light-sensitive and should be handled and stored accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥97.0%
Related Substances (HPLC)	Total impurities ≤3.0%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.