Description

2-Chloro-5-Methoxy-Pyridin-4-Ol is a versatile pyridine derivative that serves as a critical building block in advanced organic synthesis. This compound is valued for its unique halogenated and methoxylated structure, which enables precise molecular modifications. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drug candidates targeting central nervous system (CNS) disorders and infectious diseases.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides, leveraging its pyridine core for bioactivity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in metal-catalyzed cross-coupling reactions, essential for fine chemical manufacturing.
• Material Science Research: Employed in the synthesis of organic electronic materials and liquid crystals due to its electron-donating methoxy group.
• Custom Synthesis and Contract Manufacturing: A fundamental building block for custom synthesis projects and scale-up processes in CDMO (Contract Development and Manufacturing Organization) facilities.

Basic Information

Product Name	2-Chloro-5-Methoxy-Pyridin-4-Ol
CAS No.	1196145-74-0
Molecular Formula	C6H6ClNO2
Molecular Weight	159.57 g/mol
Synonyms	4-Hydroxy-2-chloro-5-methoxypyridine; 2-Chloro-5-methoxypyridin-4-ol; 5-Methoxy-2-chloropyridin-4-ol; 2-Chloro-5-methoxy-4-hydroxypyridine; 4-Pyridinol, 2-chloro-5-methoxy-; 2-Chloro-5-methoxy-4(1H)-pyridinone (tautomer); 2-Chloro-5-methoxy-4-pyridone
EINECS	Contact for details

Quality Control

Our 2-Chloro-5-Methoxy-Pyridin-4-Ol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and commercial synthesis. Certificates of Analysis (COA) with full traceability are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat sources and incompatible materials. The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.