Description

(1R,3R,4R)-(-)-3,5-Dinitrobenzoate Menthol is a high-purity chiral derivative of menthol, specifically functionalized at the hydroxyl group. This compound is a critical chiral intermediate and analytical standard, valued for its defined stereochemistry and reactivity. It is primarily used by research institutions and manufacturers in the pharmaceutical, flavor & fragrance, and fine chemical industries for asymmetric synthesis, chiral resolution, and as a reference material for quality control.

Application

• Chiral Intermediate in Pharmaceutical Synthesis: Used in the asymmetric synthesis of active pharmaceutical ingredients (APIs) requiring specific stereochemistry.
• Chiral Derivatizing Agent (CDA): Employed in analytical chemistry to separate and quantify enantiomers of chiral compounds via HPLC or NMR.
• Reference Standard: Serves as a high-purity certified reference material (CRM) for method validation and quality assurance in analytical laboratories.
• Flavor and Fragrance Chemistry: Acts as a precursor for synthesizing novel, stereochemically pure aroma chemicals and flavor modifiers.
• Academic and Industrial Research: Utilized in methodological development for catalysis and stereoselective reactions.
• Process Chemistry Development: Applied in scaling up and optimizing synthetic routes for chiral molecules.

Basic Information

Product Name	(1R,3R,4R)-(-)-3,5-Dinitrobenzoate Menthol
CAS No.	1195710-85-0
Molecular Formula	C18H24N2O6
Molecular Weight	364.40 g/mol
Synonyms	(-)-Menthyl 3,5-Dinitrobenzoate; (1R,2S,5R)-Menthyl 3,5-Dinitrobenzoate; L-Menthyl 3,5-Dinitrobenzoate; (1R,3R,4R)-2-Isopropyl-5-methylcyclohexyl 3,5-dinitrobenzoate; 3,5-Dinitrobenzoic Acid (-)-Menthyl Ester; Chiral Menthyl Dinitrobenzoate; DNB-Menthol; Menthol DNB Ester
EINECS	Contact for details

Quality Control

Our (1R,3R,4R)-(-)-3,5-Dinitrobenzoate Menthol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the stringent requirements for research and process applications. A detailed Certificate of Analysis (COA) providing purity, enantiomeric excess, and identification data is supplied with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.