Description

8-Bromo-2-Methylimidazo[1,2-A]Pyridine is a high-purity brominated heterocyclic building block of significant importance in advanced organic synthesis. This compound matters as a versatile intermediate, enabling the construction of complex molecular architectures through cross-coupling and functional group transformations. It is primarily needed by pharmaceutical R&D teams and fine chemical manufacturers for applications in medicinal chemistry, particularly in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of drug candidates targeting various therapeutic areas, including CNS disorders and infectious diseases.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its heterocyclic core for bioactivity.
• Material Science: Serves as a building block for organic electronic materials, such as ligands for OLEDs and other functional polymers.
• Chemical Biology: Employed in the design and synthesis of molecular probes and tool compounds for biological target validation.
• Cross-Coupling Reactions: The bromine substituent makes it an excellent substrate for Suzuki, Buchwald-Hartwig, and other palladium-catalyzed coupling reactions.
• Academic & Contract Research: Utilized in university and CRO laboratories for methodological development and library synthesis.

Basic Information

Product Name	8-Bromo-2-Methylimidazo[1,2-A]Pyridine
CAS No.	1194374-75-8
Molecular Formula	C8H7BrN2
Molecular Weight	211.06 g/mol
Synonyms	8-Bromo-2-methylimidazo[1,2-a]pyridine; 2-Methyl-8-bromoimidazo[1,2-a]pyridine; Imidazo[1,2-a]pyridine, 8-bromo-2-methyl-; 8-Bromo-2-methyl-imidazo[1,2-a]pyridine; 1194374-75-8
EINECS	Contact for details

Quality Control

Our 8-Bromo-2-Methylimidazo[1,2-A]Pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring traceability and consistency for critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.