Description

3,9-Diazaspiro[5.5]undecane-2,4-dione hydrochloride is a high-purity, advanced pharmaceutical intermediate with a complex spirocyclic structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated molecular scaffolds. It is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing next-generation drugs.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, especially those targeting neurological and metabolic disorders.
• Medicinal Chemistry Research: Used as a versatile scaffold for constructing novel chemical libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• API Development: Serves as a core structural component in the development of new Active Pharmaceutical Ingredients (APIs) with potential protease or receptor modulating activity.
• Chemical Synthesis: Employed in advanced organic synthesis for constructing spirocyclic and bridged heterocyclic compounds.
• Contract Research & Manufacturing (CRAM): Supplied to organizations specializing in custom synthesis and scale-up services for the pharmaceutical industry.

Basic Information

Product Name	3,9-Diazaspiro[5.5]undecane-2,4-dione hydrochloride
CAS No.	1193388-13-4
Molecular Formula	C9H14ClN2O2
Molecular Weight	218.67 g/mol
Synonyms	3,9-Diazaspiro[5.5]undecane-2,4-dione HCl; 2,4-Dioxo-3,9-diazaspiro[5.5]undecane hydrochloride; Spiro[imidazolidine-4,1'-cyclohexane]-2,5-dione, 1,3-diazaspiro[4.5]decane-2,4-dione hydrochloride (related); 1,3-Diazaspiro[4.5]decane-2,4-dione hydrochloride (isomeric); Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our production of 3,9-Diazaspiro[5.5]undecane-2,4-dione hydrochloride adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. All materials are subjected to comprehensive analytical testing, including HPLC, NMR, and mass spectrometry. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.