Description

Methyl 4-Bromo-5-Fluoro-2-Hydroxy-Benzoate is a high-purity, multi-functional aromatic ester building block, essential for advanced organic synthesis. Its core value lies in providing a versatile scaffold for constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and agrochemicals. This compound is critically needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel compounds with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-inflammatory agents, and anti-infectives.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, leveraging the bioactivity of the halogenated benzoate structure.
• Liquid Crystal & OLED Material Research: Serves as a building block for advanced organic electronic materials due to its substituted aromatic core, which can influence molecular alignment and electronic properties.
• Complex Ligand & Catalyst Development: The hydroxy and ester functional groups make it a valuable starting material for synthesizing specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for use in custom synthesis projects and scale-up campaigns for client-specific molecules.

Basic Information

Product Name	Methyl 4-Bromo-5-Fluoro-2-Hydroxy-Benzoate
CAS No.	1193162-25-2
Molecular Formula	C8H6BrFO3
Molecular Weight	249.04 g/mol
Synonyms	4-Bromo-5-fluoro-2-hydroxybenzoic acid methyl ester; Methyl 4-bromo-5-fluoro-2-hydroxybenzoate; 2-Hydroxy-4-bromo-5-fluorobenzoic acid methyl ester; Benzoic acid, 4-bromo-5-fluoro-2-hydroxy-, methyl ester; Methyl 2-hydroxy-4-bromo-5-fluorobenzoate; 4-Bromo-5-fluoro-2-hydroxy-methylbenzoate; Methyl 4-bromo-5-fluorosalicylate
EINECS	Contact for details

Quality Control

Our Methyl 4-Bromo-5-Fluoro-2-Hydroxy-Benzoate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and scale-up purposes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area %)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.