Description

2-(6-(Trifluoromethyl)Pyridin-2-Yl)Propan-2-Amine is a high-purity, specialty organic compound featuring a pyridine core substituted with a trifluoromethyl group and a tertiary amine side chain. This molecular architecture makes it a valuable and versatile building block for advanced chemical synthesis, particularly in the development of novel active ingredients. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries. The compound's unique trifluoromethylated pyridine structure offers significant potential for modulating the biological activity, metabolic stability, and physicochemical properties of target molecules.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new active pharmaceutical ingredients (APIs), especially for candidates targeting central nervous system (CNS) disorders, inflammation, and infectious diseases.
• Agrochemical Synthesis: Serves as a critical precursor for creating novel herbicides, fungicides, and insecticides, where the trifluoromethyl group often enhances lipophilicity and biological activity.
• Ligand & Catalyst Development: Used in organometallic chemistry and catalysis research to develop new ligands and catalysts for asymmetric synthesis and cross-coupling reactions.
• Material Science Research: Employed in the synthesis of advanced organic materials, such as liquid crystals, organic semiconductors, and polymers with tailored electronic properties.
• Chemical Biology Probe: Utilized as a scaffold for designing molecular probes to study enzyme function and protein-protein interactions in biochemical research.

Basic Information

Product Name	2-(6-(Trifluoromethyl)Pyridin-2-Yl)Propan-2-Amine
CAS No.	1192356-25-4
Molecular Formula	C9H11F3N2
Molecular Weight	204.19 g/mol
Synonyms	2-Propan-2-yl-6-(trifluoromethyl)pyridin-2-amine; 2-Amino-2-methyl-1-[6-(trifluoromethyl)pyridin-2-yl]propane; 2-(6-(Trifluoromethyl)-2-pyridinyl)isopropylamine; α,α-Dimethyl-6-(trifluoromethyl)-2-pyridinemethanamine; 2-(6-(Trifluoromethyl)pyridin-2-yl)propan-2-amine; 2-(6-(Trifluoromethyl)-2-pyridyl)isopropylamine; 2-(6-(Trifluoromethyl)pyridin-2-yl)-2-propylamine
EINECS	Contact for details

Quality Control

Our 2-(6-(Trifluoromethyl)Pyridin-2-Yl)Propan-2-Amine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay (HPLC), identity (IR, NMR), and impurity profiles. Our quality commitment supports compliance with cGMP and ICH guidelines for advanced intermediates, ensuring reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). The product may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider using an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.