Description

tert-Butyl7-Amino-4-Oxo-3,4-Dihydrospiro[Benzo[E][1,3]Oxazine-2,4'-Piperidine]-1'-Carboxylate is a high-purity, advanced pharmaceutical intermediate featuring a complex spirocyclic and heterocyclic architecture. This compound is of significant value for medicinal chemistry research and development, serving as a critical building block for the synthesis of novel therapeutic agents. It is primarily sought after by R&D teams and process chemists in the pharmaceutical and biotechnology industries working on innovative drug candidates.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of new active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization.
• Protease Inhibitor Synthesis: Potential building block in the synthesis of compounds targeting various protease enzymes.
• Kinase Inhibitor Development: Serves as a core structure for the design and synthesis of novel kinase inhibitor candidates.
• Chemical Biology Probes: Utilized in the creation of specialized molecular probes for studying biological pathways.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and scale-up services.

Basic Information

Product Name	tert-Butyl7-Amino-4-Oxo-3,4-Dihydrospiro[Benzo[E][1,3]Oxazine-2,4'-Piperidine]-1'-Carboxylate
CAS No.	1192355-14-8
Molecular Formula	C17H23N3O3
Molecular Weight	317.38 g/mol
Synonyms	1'-Boc-7-Amino-4-oxo-3,4-dihydrospiro[benzo[e][1,3]oxazine-2,4'-piperidine]; tert-Butyl 7-amino-4-oxo-3,4-dihydro-2H-spiro[benzo[e][1,3]oxazine-2,4'-piperidine]-1'-carboxylate; 7-Amino-1'-(tert-butoxycarbonyl)-3,4-dihydrospiro[benzo[e][1,3]oxazine-2,4'-piperidin]-4-one; 1'-Boc-7-Amino-4-oxo-3,4-dihydrospiro[benzo[e][1,3]oxazine-2,4'-piperidine]; BOC-Protected Spirocyclic Oxazine Piperidine Intermediate
EINECS	Contact for details

Quality Control

Our tert-Butyl7-Amino-4-Oxo-3,4-Dihydrospiro[Benzo[E][1,3]Oxazine-2,4'-Piperidine]-1'-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This material is moisture-sensitive; keep the container tightly sealed under an inert atmosphere if specified.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.