Description

Ethyl 2-Phenoxy-5-(Trifluoromethyl)Nicotinate is a high-value, multi-functional chemical intermediate characterized by its nicotinate core and trifluoromethyl and phenoxy substituents. This compound matters for its role in facilitating complex molecular synthesis, particularly in the development of advanced active ingredients where the trifluoromethyl group is a key pharmacophore. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing novel compounds.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), especially for candidates targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Research: Serves as a precursor in the development of new-generation herbicides, fungicides, and insecticides, leveraging the bioactivity of the nicotinate and trifluoromethyl motifs.
• Material Science: Used in research for creating specialty polymers and liquid crystals, where its aromatic and fluorinated structure can impart unique thermal and optical properties.
• Organic Synthesis: Employed in cross-coupling reactions and as a scaffold for constructing complex heterocyclic compounds in academic and industrial research settings.

Basic Information

Product Name	Ethyl 2-Phenoxy-5-(Trifluoromethyl)Nicotinate
CAS No.	1192263-87-8
Molecular Formula	C15H12F3NO3
Molecular Weight	311.26 g/mol
Synonyms	Ethyl 2-phenoxy-5-(trifluoromethyl)pyridine-3-carboxylate; 5-(Trifluoromethyl)-2-phenoxynicotinic Acid Ethyl Ester; 3-Pyridinecarboxylic acid, 2-phenoxy-5-(trifluoromethyl)-, ethyl ester; Ethyl 5-(trifluoromethyl)-2-phenoxynicotinate; 2-Phenoxy-5-(trifluoromethyl)nicotinic Acid Ethyl Ester; Nicotinic acid, 2-phenoxy-5-(trifluoromethyl)-, ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 2-Phenoxy-5-(Trifluoromethyl)Nicotinate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Any single impurity ≤ 0.5%, Total impurities ≤ 1.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.