Description

Ethyl 5-Bromo-4,6-Dichloronicotinate is a high-purity halogenated nicotinate ester, a crucial advanced intermediate in modern synthetic organic chemistry. Its value lies in its versatile reactivity, serving as a key building block for constructing complex heterocyclic scaffolds found in active pharmaceutical ingredients and agrochemicals. This compound is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new active compounds.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly for kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging its halogenated pyridine core.
• Chemical Research & Development: Serves as a versatile scaffold for medicinal chemistry, enabling structure-activity relationship (SAR) studies and library synthesis.
• Material Science Precursor: Potential building block for creating functionalized ligands, organic electronic materials, and metal-organic frameworks (MOFs).
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of client-specific target molecules.

Basic Information

Product Name	Ethyl 5-Bromo-4,6-Dichloronicotinate
CAS No.	1192263-86-7
Molecular Formula	C8H6BrCl2NO2
Molecular Weight	299.95 g/mol
Synonyms	5-Bromo-4,6-dichloronicotinic acid ethyl ester; Ethyl 5-bromo-4,6-dichloropyridine-3-carboxylate; 3-Pyridinecarboxylic acid, 5-bromo-4,6-dichloro-, ethyl ester; 5-Bromo-4,6-dichloro-3-pyridinecarboxylic acid ethyl ester; 1192263-86-7; Ethyl 5-bromo-4,6-dichloronicotinate
EINECS	Contact for details

Quality Control

Our Ethyl 5-Bromo-4,6-Dichloronicotinate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥97.0% (Area %)
Purity (HPLC)	≥98.0% (Area %)
Melting Point	Contact for details
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.