Description

Ethyl 2-Cyano-5-(Trifluoromethyl)Nicotinate is a high-value, multi-functional chemical intermediate featuring a nicotinate core substituted with cyano and trifluoromethyl groups. This compound matters for its role as a critical building block in the synthesis of complex molecules, particularly in the pharmaceutical and agrochemical sectors. Industrial and R&D professionals in fine chemical synthesis, medicinal chemistry, and crop protection research need this material for developing new active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-inflammatory applications.
• Agrochemical Synthesis: Used in the development of advanced herbicides and pesticides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in catalytic processes and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of organic electronic materials and liquid crystals due to its conjugated system and electron-withdrawing substituents.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for scale-up and production under cGMP conditions.
• Academic and Industrial R&D: A versatile scaffold for medicinal chemistry programs and structure-activity relationship (SAR) studies in discovery research.

Basic Information

Item	Detail
Product Name	Ethyl 2-Cyano-5-(Trifluoromethyl)Nicotinate
CAS No.	1192263-82-3
Molecular Formula	C10H7F3N2O2
Molecular Weight	244.17 g/mol
Synonyms	5-(Trifluoromethyl)-2-cyano-nicotinic acid ethyl ester; Ethyl 5-(trifluoromethyl)-2-cyanopyridine-3-carboxylate; 2-Cyano-5-(trifluoromethyl)nicotinic Acid Ethyl Ester; 3-Pyridinecarboxylic acid, 2-cyano-5-(trifluoromethyl)-, ethyl ester; Ethyl 2-cyano-5-(trifluoromethyl)pyridine-3-carboxylate; 1192263-82-3
EINECS	Contact for details

Quality Control

Our Ethyl 2-Cyano-5-(Trifluoromethyl)Nicotinate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR for structural confirmation, and GC for residual solvent analysis, to ensure compliance with customer specifications and industry standards. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the original container tightly sealed to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.