Description

tert-Butyl 4-[(Dibenzylamino)Methyl]-4-Hydroxytetrahydro-1(2H)-Pyridinecarboxylate CAS NO 1192263-81-2 is a high-purity, advanced pharmaceutical intermediate characterized by its complex piperidine-based structure. This compound matters for its critical role as a key building block in the synthesis of sophisticated active pharmaceutical ingredients (APIs), particularly those targeting neurological and receptor-based therapies. Pharmaceutical R&D teams and fine chemical manufacturers need this material to ensure the structural integrity and efficacy of their final drug candidates.

Application

• Pharmaceutical Intermediate: A crucial building block in the multi-step synthesis of complex drug molecules, particularly for central nervous system (CNS) targets.
• API Synthesis: Used in the research and development of novel Active Pharmaceutical Ingredients (APIs), leveraging its functionalized piperidine and protected amine groups.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and the creation of new chemical entities in drug discovery pipelines.
• Process Chemistry & Scale-Up: Employed in the optimization and kilogram-scale production of candidate drugs for preclinical and clinical trials.
• Custom Synthesis: A starting material for contract research and manufacturing organizations (CROs/CMOs) producing bespoke compounds for client projects.
• Bioconjugation & Prodrug Development: The tert-butyloxycarbonyl (Boc) protecting group and hydroxyl functionality make it suitable for designing targeted drug delivery systems.

Basic Information

Product Name	tert-Butyl 4-[(Dibenzylamino)Methyl]-4-Hydroxytetrahydro-1(2H)-Pyridinecarboxylate
CAS No.	1192263-81-2
Molecular Formula	C25H34N2O3
Molecular Weight	410.55 g/mol
Synonyms	1(2H)-Pyridinecarboxylic acid, 4-[(dibenzylamino)methyl]-4-hydroxy-tetrahydro-, 1,1-dimethylethyl ester; 4-[(Dibenzylamino)methyl]-4-hydroxypiperidine-1-carboxylic acid tert-butyl ester; tert-Butyl 4-[(dibenzylamino)methyl]-4-hydroxypiperidine-1-carboxylate; Boc-4-[(dibenzylamino)methyl]-4-hydroxypiperidine; 4-(Dibenzylaminomethyl)-4-hydroxy-1-Boc-piperidine; 1-Boc-4-[(dibenzylamino)methyl]-4-hydroxypiperidine; 4-Hydroxy-4-[(N,N-dibenzylamino)methyl]piperidine-1-carboxylic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Every batch of tert-Butyl 4-[(Dibenzylamino)Methyl]-4-Hydroxytetrahydro-1(2H)-Pyridinecarboxylate is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and batch-to-batch consistency suitable for pharmaceutical R&D. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.