Description

5-(Benzyloxy)-2-(Hydroxymethyl)-3-Iodo-4(1H)-Pyridinone is a high-purity, functionalized pyridinone derivative, serving as a critical building block in advanced organic synthesis. Its molecular structure, featuring a benzyl-protected hydroxyl group and an iodine substituent, makes it a versatile intermediate for constructing complex heterocyclic systems. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators.
• Chemical Biology Probe: Serves as a scaffold for creating molecular probes to study enzyme function and biological pathways.
• Material Science: Building block for synthesizing specialized ligands and functional organic materials.
• Cross-Coupling Reactions: The iodine atom makes it a valuable substrate for palladium-catalyzed reactions like Suzuki, Sonogashira, and Heck couplings.
• Medicinal Chemistry SAR Studies: Enables structure-activity relationship (SAR) exploration by allowing further functionalization at multiple reactive sites.

Basic Information

Product Name	5-(Benzyloxy)-2-(Hydroxymethyl)-3-Iodo-4(1H)-Pyridinone
CAS No.	1192263-75-4
Molecular Formula	C13H12INO3
Molecular Weight	357.15 g/mol
Synonyms	3-Iodo-5-(benzyloxy)-2-(hydroxymethyl)-4(1H)-pyridinone; 5-Benzyloxy-2-hydroxymethyl-3-iodo-4(1H)-pyridinone; 4(1H)-Pyridinone, 5-(benzyloxy)-2-(hydroxymethyl)-3-iodo-; 3-Iodo-5-(phenylmethoxy)-2-(hydroxymethyl)-4(1H)-pyridinone; 1192263-75-4; 5-(Benzyloxy)-2-(hydroxymethyl)-3-iodopyridin-4(1H)-one
EINECS	Contact for details

Quality Control

Our 5-(Benzyloxy)-2-(Hydroxymethyl)-3-Iodo-4(1H)-Pyridinone is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development. Each lot is analyzed using advanced techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.