Description

5-Chloro-3H-Spiro[Isobenzofuran-1,4'-Piperidine] Hydrochloride is a high-purity, advanced pharmaceutical intermediate with a complex spirocyclic structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and receptor-targeted therapies. It is primarily sought by research institutions and pharmaceutical manufacturers engaged in drug discovery and process development for next-generation therapeutics.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of new drug candidates.
• Drug Discovery Scaffold: Used in medicinal chemistry for constructing complex molecular libraries targeting specific biological pathways.
• Neurological Research: Serves as a building block for compounds being investigated for CNS disorders.
• Chemical Synthesis: Employed in organic synthesis for the construction of spirocyclic and fused heterocyclic systems.
• Reference Standard: Used as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.

Basic Information

Product Name	5-Chloro-3H-Spiro[Isobenzofuran-1,4'-Piperidine] Hydrochloride
CAS No.	1190965-20-8
Molecular Formula	C13H15Cl2NO
Molecular Weight	272.17 g/mol
Synonyms	5-Chloro-3H-spiro[2-benzofuran-1,4'-piperidine] hydrochloride; 5-Chlorospiro[isobenzofuran-1(3H),4'-piperidine] hydrochloride; 1'-(5-Chloro-1,3-dihydro-2-benzofuran-1-yl)piperidine hydrochloride; Spiro[isobenzofuran-1(3H),4'-piperidine], 5-chloro-, hydrochloride; 1190965-20-8
EINECS	Contact for details

Quality Control

Our 5-Chloro-3H-Spiro[Isobenzofuran-1,4'-Piperidine] Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under inert atmosphere or in a desiccator after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.