Description

6-Bromo-3,3-dimethyl-1H-pyrrolo[3,2-b]pyridin-2(3H)-one is a high-value brominated heterocyclic building block essential for advanced organic synthesis. This compound serves as a critical intermediate in the development of novel pharmaceutical candidates, particularly in kinase inhibitor research and other targeted therapeutic areas. It is primarily sought after by research institutions, contract development and manufacturing organizations (CDMOs), and pharmaceutical companies engaged in medicinal chemistry and process R&D.

Application

• Pharmaceutical Intermediate: Key synthon for the construction of complex molecules in drug discovery programs, especially for kinase inhibitors.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization to introduce specific bromine functionality.
• Agrochemical Synthesis: Potential building block for developing new active ingredients in crop protection science.
• Material Science Precursor: Can be utilized in the synthesis of organic electronic materials and advanced polymers.
• Contract Manufacturing: Supplied to CDMOs for scale-up and production under cGMP conditions for clinical trial materials.
• Academic Research: Used in universities and research institutes for methodological studies in heterocyclic chemistry.

Basic Information

Product Name	6-Bromo-3,3-dimethyl-1H-pyrrolo[3,2-b]pyridin-2(3H)-one
CAS No.	1190862-33-9
Molecular Formula	C9H9BrN2O
Molecular Weight	241.09 g/mol
Synonyms	6-Bromo-3,3-dimethyl-2,3-dihydro-1H-pyrrolo[3,2-b]pyridin-2-one; 6-Bromo-3,3-dimethyl-1,3-dihydro-2H-pyrrolo[3,2-b]pyridin-2-one; 1190862-33-9; 6-Bromo-3,3-dimethyl-1H-pyrrolo[3,2-b]pyridin-2-one; 2H-Pyrrolo[3,2-b]pyridin-2-one, 6-bromo-1,3-dihydro-3,3-dimethyl-
EINECS	Contact for details

Quality Control

Our 6-Bromo-3,3-dimethyl-1H-pyrrolo[3,2-b]pyridin-2(3H)-one is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific client requirements for research or cGMP applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.