Description

6-Bromospiro[1H-Pyrrolo[3,2-B]Pyridine-3,4'-Oxane]-2-One is a high-purity, advanced pharmaceutical intermediate featuring a unique spirocyclic molecular architecture. This compound is of significant value for medicinal chemistry research and development, serving as a versatile building block for the synthesis of novel bioactive molecules. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and biotechnology industries for creating new drug candidates targeting a range of therapeutic areas.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel small-molecule drug candidates, particularly in oncology and CNS research.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs due to its complex, drug-like scaffold.
• Proteolysis Targeting Chimera (PROTAC) Development: Serves as a potential linker or warhead component in the design of targeted protein degraders.
• Chemical Biology Probes: Employed in the development of tool compounds for investigating biological pathways and target validation.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process scale-up for client projects.
• Academic Research: Used in university and institutional labs for exploratory synthetic chemistry and methodology development.

Basic Information

Product Name	6-Bromospiro[1H-Pyrrolo[3,2-B]Pyridine-3,4'-Oxane]-2-One
CAS No.	1190862-19-1
Molecular Formula	C11H9BrN2O2
Molecular Weight	281.11 g/mol
Synonyms	6-Bromospiro[1H-pyrrolo[3,2-b]pyridine-3,4'-oxane]-2-one; 6-Bromo-1H-spiro[pyrrolo[3,2-b]pyridine-3,4'-oxane]-2-one; 6-Bromo-1H,1'H-spiro[pyrrolo[3,2-b]pyridine-3,4'-oxane]-2-one; 6-Bromospiro(pyrrolo[3,2-b]pyridine-3,4'-oxane)-2-one; CAS 1190862-19-1
EINECS	Contact for details

Quality Control

Our 6-Bromospiro[1H-Pyrrolo[3,2-B]Pyridine-3,4'-Oxane]-2-One is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with each shipment to ensure traceability and compliance with your research or development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.