Description

6-Bromo-2',3',5',6'-Tetrahydrospiro[Indoline-3,4'-Pyran]-2-One is a high-purity, advanced pharmaceutical intermediate featuring a complex spirocyclic molecular architecture. This compound is of significant value for its role as a key synthetic building block in modern medicinal chemistry and drug discovery programs. It is primarily sought after by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutic agents, particularly those targeting central nervous system disorders.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of complex drug candidates, especially those with spirocyclic or fused heterocyclic structures.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for discovering new bioactive molecules.
• Organic Synthesis Building Block: Utilized in constructing complex molecular frameworks for academic and industrial research in organic chemistry.
• Contract Research & Development (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for the pharmaceutical industry.

Basic Information

Product Name	6-Bromo-2',3',5',6'-Tetrahydrospiro[Indoline-3,4'-Pyran]-2-One
CAS No.	1190861-43-8
Molecular Formula	C13H12BrNO2
Molecular Weight	294.15 g/mol
Synonyms	6-Bromospiro[indoline-3,4'-pyran]-2-one; 6-Bromo-2',3',5',6'-tetrahydrospiro[indole-3,4'-pyran]-2-one; 6-Bromo-2H-spiro[indole-3,4'-pyran]-2-one; 6-Bromospiro[indoline-3,4'-4H-pyran]-2-one; 6-Bromo-2',3',5',6'-tetrahydro-2H-spiro[indole-3,4'-pyran]-2-one; 1190861-43-8; Spiro[indoline-3,4'-pyran]-2-one, 6-bromo-2',3',5',6'-tetrahydro-
EINECS	Contact for details

Quality Control

Our 6-Bromo-2',3',5',6'-Tetrahydrospiro[Indoline-3,4'-Pyran]-2-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) is provided with every shipment, detailing all relevant specifications and test results.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials and sources of ignition.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.