Description

Methyl 2,3,4-Tri-o-Isobutyryl-D-Glucopyranuronate is a key, high-purity synthetic intermediate in advanced organic synthesis. This compound matters for its role as a protected glucuronic acid derivative, enabling precise chemical modifications in complex molecule construction. It is primarily needed by research chemists and process development scientists in the pharmaceutical and fine chemical industries for the synthesis of novel glycosides, prodrugs, and bioactive molecules. Its defined stereochemistry and protective groups offer critical control in multi-step synthetic pathways.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of glycosylated drugs, prodrugs, and targeted therapeutic agents.
• Carbohydrate Chemistry Research: Used in academic and industrial R&D for studying glycosylation reactions and synthesizing complex oligosaccharides.
• Prodrug Development: Serves as a precursor for creating glucuronide prodrugs designed for targeted drug delivery and activation.
• Reference Standard: Employed as an analytical standard in quality control laboratories for method development and validation.
• Fine Chemical Synthesis: Integral to the multi-step synthesis of specialty chemicals, flavors, and fragrances requiring specific sugar motifs.
• Bioconjugation: Facilitates the attachment of carbohydrate structures to proteins, peptides, or other biomolecules for diagnostic and therapeutic applications.

Basic Information

Product Name	Methyl 2,3,4-Tri-o-Isobutyryl-D-Glucopyranuronate
CAS No.	1190403-86-1
Molecular Formula	C19H30O10
Molecular Weight	418.44 g/mol
Synonyms	Methyl 2,3,4-Tri-O-isobutyryl-α/β-D-glucopyranosiduronic acid; Methyl (2,3,4-Tri-O-isobutyryl-D-glucopyranosyl)uronate; D-Glucopyranuronic acid, methyl ester, 2,3,4-triisobutyrate; Methyl 2,3,4-Tri-O-(2-methylpropanoyl)-D-glucopyranuronate; Protected Methyl D-Glucuronate
EINECS	Contact for details

Quality Control

Every batch of Methyl 2,3,4-Tri-o-Isobutyryl-D-Glucopyranuronate is produced and tested under strict quality management protocols to ensure identity, purity, and consistency. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity (typically by HPLC/NMR), identity confirmation, and impurity profiles are available upon request to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.