Description

6-Methoxy-3-Nitro-5-Azaindole is a high-purity, advanced pharmaceutical intermediate characterized by its unique azaindole scaffold. This compound is critical for medicinal chemistry research and development, serving as a versatile building block for the synthesis of novel therapeutic agents. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers focused on developing kinase inhibitors and other targeted small-molecule drugs.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those targeting specific protein kinases.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Biochemical Tool Compound: Serves as a starting material for creating labeled probes or inhibitors used in biochemical and cellular assays.
• Fine Chemical Synthesis: Employed in multi-step organic syntheses to introduce the methoxy-nitro-azaindole moiety into more complex molecular architectures.

Basic Information

Product Name	6-Methoxy-3-Nitro-5-Azaindole
CAS No.	1190320-20-7
Molecular Formula	C8H7N3O3
Molecular Weight	193.16 g/mol
Synonyms	3-Nitro-6-methoxy-1H-pyrrolo[3,2-b]pyridine; 6-Methoxy-3-nitro-1H-pyrrolo[3,2-b]pyridine; 1H-Pyrrolo[3,2-b]pyridine, 6-methoxy-3-nitro-; 5-Azaindole, 6-methoxy-3-nitro-; 6-Methoxy-3-nitropyrrolo[3,2-b]pyridine
EINECS	Contact for details

Quality Control

Our 6-Methoxy-3-Nitro-5-Azaindole is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for pharmaceutical research. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). The compound is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.