Description

6-Bromo-1H-Pyrrolo[3,2-B]Pyridin-3-Amine is a high-purity, advanced pharmaceutical intermediate and heterocyclic building block of significant commercial interest. Its core value lies in its unique fused bicyclic structure, which serves as a privileged scaffold for medicinal chemistry, enabling the synthesis of novel bioactive molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly those developing kinase inhibitors and other targeted small-molecule therapeutics.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for oncology and antiviral drug candidates.
• Medicinal Chemistry Research: Serves as a versatile building block for constructing compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• Kinase Inhibitor Development: The pyrrolopyridine core is a common motif in the design of potent and selective kinase inhibitors for targeted cancer therapies.
• Agrochemical Synthesis: Used in the research and development of novel pesticides and herbicides, leveraging its heterocyclic bioactivity.
• Chemical Biology Probes: Employed in the creation of molecular probes to study biological pathways and protein functions.
• Material Science Research: Investigated as a potential monomer or dopant for creating organic electronic materials due to its conjugated system.

Basic Information

Product Name	6-Bromo-1H-Pyrrolo[3,2-B]Pyridin-3-Amine
CAS No.	1190319-40-4
Molecular Formula	C7H6BrN3
Molecular Weight	212.05 g/mol
Synonyms	6-Bromo-1H-pyrrolo[3,2-b]pyridin-3-amine; 3-Amino-6-bromo-1H-pyrrolo[3,2-b]pyridine; 6-Bromo-3-amino-1H-pyrrolo[3,2-b]pyridine; 6-Bromo-1H-pyrrolo[3,2-b]pyridin-3-ylamine; 1190319-40-4; 6-Bromo-1H-pyrrolo[3,2-b]pyridin-3-amine (CAS 1190319-40-4); 6-Bromo-3-aminopyrrolo[3,2-b]pyridine
EINECS	Contact for details

Quality Control

Our 6-Bromo-1H-Pyrrolo[3,2-B]Pyridin-3-Amine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our commitment to quality supports compliance with cGMP and ICH guidelines for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) when not in use to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.