Description

5-Chloro-4-Fluoro-1H-Pyrrolo[2,3-B]Pyridine is a high-value, multi-functional heterocyclic building block essential for advanced organic synthesis. Its unique fused pyrrolopyridine core, functionalized with halogen substituents, makes it a critical intermediate for constructing complex molecular architectures. This compound is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of kinase inhibitors and other small-molecule therapeutics targeting various disease pathways.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its halogenated heterocyclic structure for bioactivity.
• Material Science: Acts as a building block for organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors.
• Chemical Biology: Employed as a molecular probe or scaffold in drug discovery and biochemical research.
• Custom Synthesis: Provides a versatile starting point for contract research organizations (CROs) and fine chemical manufacturers for bespoke synthesis projects.

Basic Information

Product Name	5-Chloro-4-Fluoro-1H-Pyrrolo[2,3-B]Pyridine
CAS No.	1190317-94-2
Molecular Formula	C7H4ClFN2
Molecular Weight	170.57 g/mol
Synonyms	5-Chloro-4-fluoro-1H-pyrrolo[2,3-b]pyridine; 4-Fluoro-5-chloro-1H-pyrrolo[2,3-b]pyridine; 1H-Pyrrolo[2,3-b]pyridine, 5-chloro-4-fluoro-; 5-Chloro-4-fluoro-7-azaindole; 4-Fluoro-5-chloro-7-azaindole; 5-Chloro-4-fluoro-pyrrolo[2,3-b]pyridine
EINECS	Contact for details

Quality Control

Our 5-Chloro-4-Fluoro-1H-Pyrrolo[2,3-B]Pyridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and industry best practices for research-grade chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.