Description

6-(Trifluoromethyl)-1H-Pyrrolo[3,2-C]Pyridine CAS NO 1190315-48-0 is a high-value, fluorinated heterocyclic building block essential for modern pharmaceutical and agrochemical research. Its unique pyrrolopyridine core, functionalized with a trifluoromethyl group, provides critical properties such as enhanced metabolic stability, lipophilicity, and bioavailability to target molecules. This advanced intermediate is primarily sought by medicinal chemists and process development scientists in the pharmaceutical industry for the synthesis of novel active pharmaceutical ingredients (APIs) and drug candidates.

Application

• Pharmaceutical Intermediate: A key scaffold in the research and development of new drug candidates, particularly in oncology, central nervous system (CNS) disorders, and antiviral therapies.
• Agrochemical Synthesis: Used in the design and production of novel pesticides and herbicides, where the trifluoromethyl group can improve biological activity and environmental stability.
• Material Science Research: Serves as a building block for developing specialty chemicals, organic electronic materials, and advanced polymers with specific fluorinated properties.
• Chemical Biology Probes: Employed in the synthesis of molecular probes and tool compounds for studying biological pathways and target engagement.
• Process Chemistry & Scale-up: Supplied for route scouting, optimization, and cGMP manufacturing of clinical trial materials and commercial APIs.

Basic Information

Product Name	6-(Trifluoromethyl)-1H-Pyrrolo[3,2-C]Pyridine
CAS No.	1190315-48-0
Molecular Formula	C8H5F3N2
Molecular Weight	186.14 g/mol
Synonyms	6-(Trifluoromethyl)-1H-pyrrolo[3,2-c]pyridine; 1H-Pyrrolo[3,2-c]pyridine, 6-(trifluoromethyl)-; 6-Trifluoromethyl-1H-pyrrolo[3,2-c]pyridine; 6-(Trifluoromethyl)pyrrolo[3,2-c]pyridine; 6-(Trifluoromethyl)-7-azaindole; 6-CF3-1H-pyrrolo[3,2-c]pyridine; 6-CF3-7-azaindole
EINECS	Contact for details

Quality Control

Every batch of 6-(Trifluoromethyl)-1H-Pyrrolo[3,2-C]Pyridine is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the rigorous standards required for research and development. A detailed Certificate of Analysis (COA) is supplied with each shipment, confirming identity, purity, and impurity profiles. Our quality commitment supports compliance with ISO standards and the stringent requirements of the pharmaceutical supply chain.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.