Description

1H-Pyrrolo[2,3-B]Pyridine, 5-Bromo-3-Chloro-4-Methyl- is a high-purity, multi-halogenated heterocyclic building block of significant interest in advanced organic synthesis. This compound matters because it provides a versatile and functionalized core structure for constructing complex molecules, enabling the exploration of novel chemical space. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications in medicinal chemistry, including the development of new active pharmaceutical ingredients (APIs) and crop protection agents.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel drug candidates, particularly kinase inhibitors and other targeted therapies.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and library synthesis in early-stage drug discovery.
• Agrochemical Development: Acts as a key building block for creating new herbicides, fungicides, and insecticides with potentially improved efficacy.
• Material Science Research: Employed in the development of advanced organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors.
• Chemical Biology Probes: Utilized to create labeled compounds or molecular probes for studying biological pathways and target engagement.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds at various scales.

Basic Information

Product Name	1H-Pyrrolo[2,3-B]Pyridine, 5-Bromo-3-Chloro-4-Methyl-
CAS No.	1190314-14-7
Molecular Formula	C8H6BrClN2
Molecular Weight	245.50 g/mol
Synonyms	5-Bromo-3-chloro-4-methyl-1H-pyrrolo[2,3-b]pyridine; 4-Methyl-5-bromo-3-chloro-1H-pyrrolo[2,3-b]pyridine; 3-Chloro-5-bromo-4-methyl-1H-pyrrolo[2,3-b]pyridine; 5-Bromo-3-chloro-4-methyl-7-azaindole; 7-Azaindole, 5-bromo-3-chloro-4-methyl-; 1H-Pyrrolo[2,3-b]pyridine, 5-bromo-3-chloro-4-methyl-; 5-Bromo-3-chloro-4-methyl-1H-pyrrolo[2,3-b]pyridine
EINECS	Contact for details

Quality Control

Our 1H-Pyrrolo[2,3-B]Pyridine, 5-Bromo-3-Chloro-4-Methyl- is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to supply chain integrity and batch-to-batch reproducibility makes us a reliable partner for your critical R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive); therefore, containers should be kept sealed under an inert atmosphere when not in use to prevent degradation. Keep away from strong acids/bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.