Description

3-Chloro-4-Azaindole-7-Carboxylic Acid is a high-purity, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in its unique molecular scaffold, which serves as a privileged structure for designing novel bioactive compounds. This intermediate is primarily targeted at research and development teams within the pharmaceutical and agrochemical industries, where it is used to create new drug candidates and active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in the synthesis of novel herbicides and fungicides with targeted modes of action.
• Chemical Biology: Serves as a versatile scaffold for constructing molecular probes and tool compounds.
• Material Science: Potential precursor for the synthesis of specialized organic electronic materials and ligands for catalysis.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development.

Basic Information

Product Name	3-Chloro-4-Azaindole-7-Carboxylic Acid
CAS No.	1190312-92-5
Molecular Formula	C8H5ClN2O2
Molecular Weight	196.59 g/mol
Synonyms	7-Carboxy-3-chloro-1H-pyrrolo[2,3-b]pyridine; 3-Chloro-1H-pyrrolo[2,3-b]pyridine-7-carboxylic acid; 3-Chloro-4-aza-7-indolecarboxylic acid; 3-Chloro-4-azaindole-7-carboxylate; 3-Cl-4-Aza-7-IndCOOH; AZD-1480 Intermediate; JAK2 Inhibitor Intermediate
EINECS	Contact for details

Quality Control

Our 3-Chloro-4-Azaindole-7-Carboxylic Acid is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. Certificates of Analysis (COA) documenting all specifications are provided and available upon request to ensure full traceability and compliance with your project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if necessary for long-term storage.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.