Description

1H-Pyrrolo[3,2-B]Pyridine-6-Carboxylic Acid, 2,3-Dihydro-2-Oxo-, Methyl Ester is a high-purity heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel pharmaceutical agents, particularly in medicinal chemistry research. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for kinase inhibitors and other targeted therapies.
• Medicinal Chemistry Research: Used as a versatile scaffold for constructing and screening novel drug candidates in hit-to-lead and lead optimization programs.
• Agrochemical Synthesis: Employed in the development of new generation herbicides and fungicides that require complex heterocyclic cores.
• Fine Chemical Production: Acts as a building block for specialty chemicals, dyes, and advanced materials requiring specific fused ring systems.
• Academic & Contract Research: Utilized in university and CRO (Contract Research Organization) laboratories for methodological studies and novel compound library generation.

Basic Information

Product Name	1H-Pyrrolo[3,2-B]Pyridine-6-Carboxylic Acid, 2,3-Dihydro-2-Oxo-, Methyl Ester
CAS No.	1190312-75-4
Molecular Formula	C9H8N2O3
Molecular Weight	192.17 g/mol
Synonyms	Methyl 2-oxo-2,3-dihydro-1H-pyrrolo[3,2-b]pyridine-6-carboxylate; 1H-Pyrrolo[3,2-b]pyridine-6-carboxylic acid, 2,3-dihydro-2-oxo-, methyl ester; 6-(Methoxycarbonyl)-2,3-dihydro-1H-pyrrolo[3,2-b]pyridin-2-one; Methyl 2-oxo-1,2-dihydropyrrolo[3,2-b]pyridine-6-carboxylate
EINECS	Contact for details

Quality Control

Our 1H-Pyrrolo[3,2-B]Pyridine-6-Carboxylic Acid, 2,3-Dihydro-2-Oxo-, Methyl Ester is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) are provided with each shipment, detailing all critical quality attributes. We support cGMP compliance for pharmaceutical applications and can tailor specifications to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maximize stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.