Description

3-Bromo-5-Chloro-1H-Pyrrolo[3,2-B]Pyridine is a high-value halogenated heterocyclic building block essential for advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel pharmaceuticals and agrochemicals, enabling precise molecular modifications. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating complex, functionalized molecules.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its halogenated pyrrolopyridine scaffold.
• Material Science: Serves as a building block for creating organic electronic materials, such as ligands for OLEDs or conductive polymers.
• Chemical Biology: Employed in the design and synthesis of molecular probes and tool compounds for target validation and mechanistic studies.
• Academic & Contract Research: Utilized in university and CRO laboratories for methodological development and exploring new chemical spaces.
• Custom Synthesis: A starting material for contract manufacturing organizations (CMOs) producing bespoke compounds for client projects.

Basic Information

Product Name	3-Bromo-5-Chloro-1H-Pyrrolo[3,2-B]Pyridine
CAS No.	1190310-75-8
Molecular Formula	C7H4BrClN2
Molecular Weight	231.48 g/mol
Synonyms	3-Bromo-5-chloro-1H-pyrrolo[3,2-b]pyridine; 1H-Pyrrolo[3,2-b]pyridine, 3-bromo-5-chloro-; 5-Chloro-3-bromo-1H-pyrrolo[3,2-b]pyridine; 3-Bromo-5-chloro-7-azaindole; 5-Chloro-3-bromo-7-azaindole; 3-Br-5-Cl-1H-pyrrolo[3,2-b]pyridine; 3-Bromo-5-chloro-pyrrolo[3,2-b]pyridine
EINECS	Contact for details

Quality Control

Our 3-Bromo-5-Chloro-1H-Pyrrolo[3,2-B]Pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) with full characterization data are available upon request. We support development from research to commercial scale with quality standards suitable for cGMP applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.