Description

5-Chloro-3-Iodo-1H-Pyrrolo[2,3-C]Pyridine is a high-value halogenated heterocyclic building block of significant interest in advanced organic synthesis. Its core structure, featuring both chlorine and iodine substituents on the fused pyrrolopyridine scaffold, makes it a versatile intermediate for constructing complex molecular architectures. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the discovery and development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in kinase inhibitor research and other targeted therapies.
• Agrochemical Research: Serves as a building block for developing new herbicides, fungicides, and insecticides with unique modes of action.
• Material Science: Used in the development of organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors, due to its electron-rich heterocyclic core.
• Chemical Biology: Employed as a molecular probe or a tag in bioconjugation chemistry and proteomics research.
• Cross-Coupling Reactions: The iodine substituent makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) to introduce complex functionalities.
• Ligand Synthesis: Acts as a starting material for the preparation of novel nitrogen-containing ligands for catalysis.

Basic Information

Product Name	5-Chloro-3-Iodo-1H-Pyrrolo[2,3-C]Pyridine
CAS No.	1190310-51-0
Molecular Formula	C7H4ClIN2
Molecular Weight	278.48 g/mol
Synonyms	5-Chloro-3-iodo-1H-pyrrolo[2,3-c]pyridine; 1H-Pyrrolo[2,3-c]pyridine, 5-chloro-3-iodo-; 3-Iodo-5-chloro-1H-pyrrolo[2,3-c]pyridine; 5-Chloro-3-iodo-7-azaindole; 3-Iodo-5-chloro-7-azaindole
EINECS	Contact for details

Quality Control

Our 5-Chloro-3-Iodo-1H-Pyrrolo[2,3-C]Pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to quality supports research reproducibility and process development from discovery to scale-up.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.