Description

2-Thiophenecarboxylic Acid, 5-[3-(Trifluoromethyl)Phenyl]-, Ethyl Ester is a high-value, multi-functional heterocyclic building block designed for advanced chemical synthesis. This compound is engineered to provide a unique combination of a thiophene core and a trifluoromethylphenyl moiety, offering significant potential for modulating the physicochemical properties of target molecules. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the creation of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in areas targeting CNS disorders, inflammation, and oncology.
• Agrochemical Research: Used in the synthesis of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Material Science: Serves as a precursor for functional polymers, liquid crystals, and organic electronic materials due to its conjugated thiophene system.
• Chemical Synthesis: Acts as a versatile building block in organic chemistry for constructing complex heterocyclic frameworks via cross-coupling and cyclization reactions.
• Dye & Pigment Industry: Potential intermediate for the synthesis of specialized dyes and pigments with unique color and light-fastness properties.

Basic Information

Product Name	2-Thiophenecarboxylic Acid, 5-[3-(Trifluoromethyl)Phenyl]-, Ethyl Ester
CAS No.	1190235-26-7
Molecular Formula	C14H11F3O2S
Molecular Weight	300.30 g/mol
Synonyms	Ethyl 5-[3-(Trifluoromethyl)phenyl]thiophene-2-carboxylate; 5-(3-Trifluoromethylphenyl)thiophene-2-carboxylic Acid Ethyl Ester; 2-Thiophenecarboxylic acid, 5-[3-(trifluoromethyl)phenyl]-, ethyl ester; Ethyl 5-(3-(trifluoromethyl)phenyl)thiophene-2-carboxylate; 5-(3-Trifluoromethyl-phenyl)-thiophene-2-carboxylic acid ethyl ester
EINECS	Contact for details

Quality Control

Our 2-Thiophenecarboxylic Acid, 5-[3-(Trifluoromethyl)Phenyl]-, Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents and incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥97.0%
Related Substances (HPLC)	Total impurities ≤3.0%
Residual Solvents (GC)	Complies with ICH guidelines
Melting Point	Contact for details
Loss on Drying	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.