Description

Ethyl(5-Ethyl-2-Pyridinyl)-1,1-D2-Acetate is a deuterated organic compound, specifically an isotopically labeled ethyl acetate derivative featuring a pyridine ring. This deuteration is critical for applications requiring enhanced metabolic stability, reduced toxicity, or as a non-radioactive tracer in research. It serves as a valuable synthetic intermediate and reference standard in pharmaceutical development and advanced chemical research. Key industries that utilize this specialty chemical include pharmaceutical R&D, agrochemical synthesis, and academic research institutions focused on mechanistic studies and analytical method development.

Application

• Pharmaceutical Intermediate: Used in the synthesis of deuterated drug candidates to improve pharmacokinetic profiles, such as metabolic stability and bioavailability.
• Metabolic Studies: Acts as a stable isotope-labeled internal standard in Liquid Chromatography-Mass Spectrometry (LC-MS) for accurate quantification and metabolite tracking.
• Mechanistic Research: Employed in chemical and biochemical research to investigate reaction pathways and mechanisms using Isotope Effects.
• Agrochemical Development: Serves as a building block for creating novel, deuterated active ingredients with potentially improved environmental persistence or efficacy.
• Analytical Reference Standard: Provides a high-purity certified material for calibrating analytical instruments and validating methods in quality control laboratories.
• Material Science: Investigated for potential use in the synthesis of advanced organic materials, such as ligands for catalysis or components for organic electronics.

Basic Information

Item	Details
Product Name	Ethyl(5-Ethyl-2-Pyridinyl)-1,1-D2-Acetate
CAS No.	1189654-25-8
Molecular Formula	C11H13D2NO2
Molecular Weight	195.26 g/mol (approx.)
Synonyms	1,1-Dideutero-ethyl 2-(5-ethylpyridin-2-yl)acetate; Ethyl 2-(5-Ethyl-2-pyridinyl)-1,1-d2-acetate; Deuterated Ethyl 5-Ethylpicolinate Derivative; (5-Ethyl-2-pyridyl)-1,1-d2-acetic Acid Ethyl Ester; 2-(5-Ethylpyridin-2-yl)-1,1-d2-ethyl acetate; Ethyl (5-Ethylpyridin-2-yl)-1,1-d2-acetate; [1,1-2H2]-Ethyl 2-(5-ethyl-2-pyridinyl)acetate
EINECS	Contact for details

Quality Control

Our Ethyl(5-Ethyl-2-Pyridinyl)-1,1-D2-Acetate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR (¹H & ²H) for isotopic enrichment verification and HPLC for chemical purity assessment, to ensure compliance with precise customer specifications. Certificates of Analysis (COA) detailing batch-specific results for identity, purity, isotopic content, and impurities are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to moisture. Store away from strong bases and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Isotopic Enrichment (²H NMR)	≥ 98.0 atom % D
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.