Description

1-(3-Methyl-4-Nitrophenyl)Piperidine-2-Carboxylic Acid is a specialized organic compound featuring a piperidine carboxylic acid core substituted with a methyl-nitrophenyl group, making it a valuable chiral building block and intermediate in advanced synthesis. Its precise molecular architecture is critical for constructing complex pharmacophores, particularly in the development of active pharmaceutical ingredients (APIs) and fine chemicals. This high-purity intermediate is essential for research and production chemists in the pharmaceutical, agrochemical, and advanced material science industries seeking to introduce specific steric and electronic properties into target molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel therapeutic agents, particularly for central nervous system (CNS) targets and enzyme inhibitors.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides where the nitrophenyl and piperidine motifs contribute to biological activity.
• Organic Light-Emitting Diode (OLED) Materials: Serves as a precursor for electron-transport or host materials in the manufacture of high-performance display and lighting technologies.
• Ligand and Catalyst Development: Employed in the synthesis of complex ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Academic and Industrial R&D: A crucial compound for methodological studies in organic chemistry, including novel coupling reactions and heterocycle functionalization.
• Fine Chemical Production: Used in the custom synthesis of complex, high-value molecules for specialty chemical applications.

Basic Information

Product Name	1-(3-Methyl-4-Nitrophenyl)Piperidine-2-Carboxylic Acid
CAS No.	1189547-44-1
Molecular Formula	C14H18N2O4
Molecular Weight	278.31 g/mol
Synonyms	2-Piperidinecarboxylic acid, 1-(3-methyl-4-nitrophenyl)-; 1-(3-Methyl-4-nitrophenyl)piperidine-2-carboxylic acid; 1-(3-Methyl-4-nitrophenyl)-2-piperidinecarboxylic acid; (3-Methyl-4-nitrophenyl)piperidine-2-carboxylic acid; 1189547-44-1; 1-(3-Methyl-4-nitro-phenyl)-piperidine-2-carboxylic acid; 1-(3-Methyl-4-nitrophenyl)piperidine-2-carboxylate
EINECS	Contact for details

Quality Control

Our production of 1-(3-Methyl-4-Nitrophenyl)Piperidine-2-Carboxylic Acid adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation via NMR and mass spectrometry. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment, and we support compliance with cGMP, ISO, and REACH standards for global supply.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be light-sensitive; prolonged exposure to light should be avoided. Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.