Description

(E)-2-((tert-Butyldimethylsilyloxy)Methyl)-Furo[3,2-B]Pyridine-6-Carbaldehyde Oxime is a high-purity, advanced pharmaceutical intermediate characterized by its unique fused heterocyclic structure. This compound is of significant value for its role as a key synthetic building block in the research and development of novel active pharmaceutical ingredients (APIs). It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers engaged in the synthesis of complex molecules for therapeutic applications.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of potential drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Organic Synthesis Building Block: Used in complex organic transformations, including cross-coupling reactions and functional group manipulations, due to its reactive oxime and protected silyl ether groups.
• Medicinal Chemistry Research: Serves as a scaffold for structure-activity relationship (SAR) studies to optimize the potency and selectivity of lead compounds.
• Process Chemistry Development: Employed in scaling up synthetic routes from laboratory to pilot plant and commercial manufacturing scales.
• Contract Research & Manufacturing (CRAM): Supplied to organizations providing custom synthesis and process development services for the global pharmaceutical industry.

Basic Information

Product Name	(E)-2-((tert-Butyldimethylsilyloxy)Methyl)-Furo[3,2-B]Pyridine-6-Carbaldehyde Oxime
CAS No.	1189170-70-4
Molecular Formula	C16H24N2O3Si
Molecular Weight	320.46 g/mol
Synonyms	(E)-2-(((tert-Butyldimethylsilyl)oxy)methyl)furo[3,2-b]pyridine-6-carbaldehyde oxime; 2-[(Tert-Butyldimethylsilyloxy)Methyl]Furo[3,2-B]Pyridine-6-Carbaldehyde Oxime; Furo[3,2-b]pyridine-6-carboxaldehyde, 2-[[(1,1-dimethylethyl)dimethylsilyl]oxy]methyl]-, oxime; TBDMS-protected furopyridine oxime; 1189170-70-4; (E)-6-((Hydroxyimino)methyl)-2-(((tert-butyldimethylsilyl)oxy)methyl)furo[3,2-b]pyridine
EINECS	Contact for details

Quality Control

Our (E)-2-((tert-Butyldimethylsilyloxy)Methyl)-Furo[3,2-B]Pyridine-6-Carbaldehyde Oxime is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is easily oxidized and should be stored under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep the container tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.