Description

2-Naphthyl (1R,4R,7R)-7-Isopropyl-5-Methylbicyclo[2.2.2]Octa-2,5-Diene-2-Carboxylate is a high-purity, stereochemically defined chiral intermediate of significant interest in advanced organic synthesis. This compound matters for its role as a sophisticated building block in the development of complex, biologically active molecules, offering precise structural control. It is primarily needed by research and development teams in the pharmaceutical and agrochemical industries, where it serves as a key precursor for novel active ingredients and fine chemical synthesis.

Application

• Pharmaceutical Intermediate: A critical chiral building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting complex molecular architectures.
• Agrochemical Research: Used in the development of advanced, stereoselective pesticides and herbicides where specific spatial orientation is crucial for biological activity.
• Asymmetric Catalysis Ligand Precursor: Serves as a starting material for the synthesis of novel chiral ligands used in asymmetric hydrogenation and other catalytic transformations.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of specialty chemicals, flavors, and fragrances requiring high stereochemical purity.
• Academic & Industrial R&D: A valuable tool for chemists in universities and corporate labs exploring new synthetic methodologies and complex natural product analogs.
• Material Science Research: Potential precursor for chiral organic frameworks or advanced polymeric materials with specific optical properties.

Basic Information

Product Name	2-Naphthyl (1R,4R,7R)-7-Isopropyl-5-Methylbicyclo[2.2.2]Octa-2,5-Diene-2-Carboxylate
CAS No.	1188966-75-7
Molecular Formula	C24H26O2
Molecular Weight	346.47 g/mol
Synonyms	(1R,4R,7R)-7-Isopropyl-5-methylbicyclo[2.2.2]octa-2,5-diene-2-carboxylic acid 2-naphthyl ester; 2-Naphthyl 7-isopropyl-5-methylbicyclo[2.2.2]octa-2,5-diene-2-carboxylate (specifying (1R,4R,7R) stereochemistry); Bicyclo[2.2.2]octadiene naphthyl ester derivative; Chiral bicyclic naphthyl ester; (1R,4R,7R)-Tricyclic ester intermediate; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our 2-Naphthyl (1R,4R,7R)-7-Isopropyl-5-Methylbicyclo[2.2.2]Octa-2,5-Diene-2-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and process development. Certificates of Analysis (COA) detailing identity, purity, and stereochemical integrity are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep the container tightly sealed under an inert atmosphere to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.