Description

2-((tert-Butyldimethylsilyloxy)Methyl)-6-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Furo[3,2-B]Pyr is a high-value, multi-functional heterocyclic building block that combines a protected hydroxymethyl group with a boronic ester moiety. This compound matters as a critical synthetic intermediate, enabling precise Suzuki-Miyaura cross-coupling reactions for constructing complex molecular architectures. Pharmaceutical, agrochemical, and advanced materials researchers need it for the efficient synthesis of novel active ingredients and functional organic compounds.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing novel drug candidates, particularly in medicinal chemistry programs targeting complex heterocyclic cores.
• Agrochemical Synthesis: Used in the research and development of new active ingredients for crop protection and pest management.
• Material Science Research: Serves as a precursor for organic electronic materials, such as OLEDs and organic semiconductors, due to its fused furan-pyrrole structure.
• Suzuki-Miyaura Cross-Coupling: The pinacol boronate ester functionality enables efficient palladium-catalyzed carbon-carbon bond formation with aryl/heteroaryl halides.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and labeled compounds for biological studies.
• Ligand and Catalyst Development: Acts as a starting material for creating novel ligands and organometallic catalysts.

Basic Information

Item	Details
Product Name	2-((tert-Butyldimethylsilyloxy)Methyl)-6-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Furo[3,2-B]Pyr
CAS No.	1188927-49-2
Molecular Formula	C20H36BNO4Si
Molecular Weight	393.41 g/mol
Synonyms	2-((tert-Butyldimethylsilyloxy)methyl)-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)furo[3,2-b]pyrrole; 6-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-(((tert-butyldimethylsilyl)oxy)methyl)furo[3,2-b]pyrrole; 2-(((tert-Butyldimethylsilyl)oxy)methyl)-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)furo[3,2-b]pyrrole; Furo[3,2-b]pyrrole-2-methanol, 6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-, 1-(1,1-dimethylethyl)dimethylsilyl ether; TBS-protected furo[3,2-b]pyrrole boronic ester; Bpin-furo[3,2-b]pyrrole-TBS ether
EINECS	Contact for details

Quality Control

Our 2-((tert-Butyldimethylsilyloxy)Methyl)-6-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Furo[3,2-B]Pyr is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and LC-MS, to ensure high purity and structural identity. Certificates of Analysis (COA) with detailed chromatographic and spectroscopic data are provided to guarantee batch-to-batch consistency and support your R&D and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥95% (Area %)
Water Content (KF)	≤0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.