Description

5-Bromo-6-(2,2,2-trifluoroethoxy)-2-(trifluoromethyl)nicotinic acid is a high-value, multi-fluorinated nicotinic acid derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both bromo and trifluoromethoxy/trifluoromethyl substituents, makes it indispensable for introducing specific steric and electronic properties into target molecules. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, particularly in areas targeting metabolic and central nervous system disorders.
• Agrochemical Research: Used in the synthesis of novel herbicides and pesticides, where the fluorine atoms enhance biological activity and environmental stability.
• Material Science Precursor: Employed in the research of advanced organic electronic materials and liquid crystals due to its fluorinated aromatic core.
• Chemical Biology Probe: Serves as a building block for creating labeled compounds or molecular probes used in biochemical assays and diagnostic research.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences industry.

Basic Information

Product Name	5-Bromo-6-(2,2,2-trifluoroethoxy)-2-(trifluoromethyl)nicotinic Acid
CAS No.	1188926-14-8
Molecular Formula	C10H4BrF6NO3
Molecular Weight	356.04 g/mol
Synonyms	5-Bromo-6-(2,2,2-trifluoroethoxy)-2-(trifluoromethyl)pyridine-3-carboxylic acid; 3-Pyridinecarboxylic acid, 5-bromo-6-(2,2,2-trifluoroethoxy)-2-(trifluoromethyl)-; 1188926-14-8; 5-Bromo-6-(2,2,2-trifluoroethoxy)-2-trifluoromethylnicotinic acid; Nicotinic acid, 5-bromo-6-(2,2,2-trifluoroethoxy)-2-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Every batch of 5-Bromo-6-(2,2,2-trifluoroethoxy)-2-(trifluoromethyl)nicotinic acid is produced and tested under strict quality management protocols to ensure consistency and purity for research and development applications. Our standard analytical package includes identity confirmation by spectroscopic methods (NMR, IR) and purity determination by HPLC. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment to support your regulatory and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.